Monday, April 21, 2014

Testing For Early-Onset Alzheimer’s Disease

A form of dementia, early-onset Alzheimer’s disease typically affects people in their 50s, though it is seen in persons as young as their 30s. Unlike Alzheimer’s that affects those over age 65,
early-onset AD has been linked to inherited genetics, and frequently runs in families.  Recent studies on this disease have shown promise in helping detect it's condition and finding new treatments. The following are 5 recent breakthroughs:

1. Blood Test Detects Early-Onset Alzheimer’s - Researchers at Georgetown University and the University of Rochester have developed a blood test that indicates risks for Alzheimer’s. The test examines the amounts of certain fats in the bloodstream. Based on clinical trials, the test shows with ~90% accuracy of the likelihood of developing Alzheimer’s within the next three years. It should be cautioned that this test requires further work before it can be applied outside of clinical trials.

2. Eye Test Could Diagnose Alzheimer’s Years Before Symptoms Occur - Sapphire II, an eye exam technology, could diagnose Alzheimer’s in a matter of minutes. Developed by Cognoptix, Sapphire II is a laser-based reading device and consumable ophthalmic ointment.  Cognoptix is seeking FDA approval to use the test to help physicians diagnose suspected cases of Alzheimer’s.

3. SAGE, A Self-Test for Alzheimer’s - A 12-question test, the Self-Administered Gerocognitive Examination (SAGE) may help spot cognitive decline in as little as 15 minutes. Ohio State University developed the test and administered it to over 1,000 research participants. Results showed that 28% of test takers demonstrated symptoms of cognitive decline, which correlated to more detailed cognitive testing. Ideally, a person whose score signaled potential cognitive decline would go their doctor sooner for a diagnosis. The test should be viewed as a baseline for cognitive function and is not a substitute for a medical exam, but is a usefull diagnosis tool.

4. An App for Detecting Alzheimer’s - In this day of "An App For Everything", there is Neuroracer.  Developed by Alkili Interactive Labs, it may help detect early signs of Alzheimer’s. Alkili conducted a study with Neuroracer that showed it improved brain activity and multitasking skills for older players. The hope is that the app could become a benchmark for other testing and pave the way for more mobile video games that could serve as medical tools.

5. Peanut Butter Exam May Diagnose Alzheimer’s - Looking to link sense of smell to cognitive decline, researchers from the University of Florida have discovered that patients diagnosed with early stage Alzheimer's diagnosis will struggle to smell a spoonful of peanut butter. Because sense of smell often fails early on for Alzheimer’s patients, researchers believe this tests fo this nature could become a valuable tool in early detection.

Experts warn that simple tests for diagnosing such a complex disease are not always accurate.  The ongoing research that produces these is encouraging though. As with any health question, always consult with your physician with any health concerns.

Bringing useful news to educate our clients is one more way that Home Helpers has been making life easier for over a decade.  Call us today at 704-909-7958.  And as always, you can find us on our websiteFacebook and

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